Qi is one of Chinese Medicine's vital subtances. Design of Animal Experiment. NC Neighbor Connectivity. Representations Herbal products are food supplements. Coronary artery disease, angina and other cardiovascular issues. Peng, W. H., Tien, Y. C., Huang, C. Y., Huang, T. H., Liao, J. C., Kuo, C. L., et al. As such Ge Xia Zhu Yu Tang is used by TCM practitioners to treat four different patterns which we describe below. 0 statistical software package. Then, TNF signaling induces biological effects as diverse as cell proliferation, metabolic activation, inflammatory response, and cell apoptotic or necrotic. The fibrosis quantification of the sirius red staining representative images was performed in 5 random fields of each mouse under ×200 magnification (Scale bars = 100 μm, n = 6). Chen, J. Y., Chen, H. L., Cheng, J. C., Lin, H. J., Tung, Y. T., Lin, C. F., et al. Wu Ling Zhi (Feces Trogopterori). The DisGeNET Knowledge Platform for Disease Genomics: 2019 Update.
TCMSP: a Database of Systems Pharmacology for Drug Discovery from Herbal Medicines. Hui, T., Bai, G., and Liu, F. (2016). And the results of the cell experiment showed that GXZY could inhibit the proliferation and migration of human HSC. Rather, Ge Xia Zhu Yu Tang is used to treat patterns that are sometimes the root cause behind scanty menstruation. Page: The following combinations are available for this ingredient. The overlapped genes (OGEs) were the intersection of the GXZY compound-putative targets and LC disease targets. The Liver is a so-called "Zang" Organ. Secretary of Commerce. TCVM PRINCIPLES: Invigorates Qi/Blood and relieves pain. Wu Yao, Yan Hu Suo, Zhi Qiao and Xiang Fu: promoting the circulation of qi and blood, alleviating pain.
Szklarczyk, D., Gable, A. L., Lyon, D., Junge, A., Wyder, S., Huerta-Cepas, J., et al. Items originating outside of the U. that are subject to the U. A modified four-point gait. Consultation Support. Collection of Chemical Compounds in GXZY. HE was used to observe the morphological changes of liver and Sirius red staining observe the deposition of collagen fibers in the liver between groups. TNF-α could induce the phosphorylation of ERK and JNK in LX-2 cells, and induce the expression of inflammatory cytokines such as IL-1β and IL-6 (Pan et al., 2019). 1186/1471-2164-16-s3-s1. Subcategories & Applications. Our clinical staff have made the following notes, regarding ge xia zhu yu wan. Product Search Results. The representative images of cell migration assay for LX-2 cells.
With Wu Yao, disperses Cold and stops pain, for abdominal pain due to External Cold and cold dysmenorrhea or postpartum abdominal pain. ""Decoction"" for chasing stagnation under the diaphragm. REGISTERED CUSTOMERS. Therefore, it is challenging to study the pharmacological mechanisms of GXZY in the treatment of liver diseases. Effects: activating blood to dispel stasis; moving qi and relieving pain. Disperse blood stasis, alleviate pain - amenorrhea, dysmenorrhea, post partum abdominal pain, epigastric pain due to blood stasis. I. e., in the epigastrium) manifesting as abdominal distention and pain, abdominal tumors, hepatomegaly, splenomegaly, dysmenorrhea, amenorrhea, irregular menstruation, hiatal hernia, etc.
Finally, the experiments of Western Blotting and qRT-PCR were used to verify the expression of key target genes. T000200116, Neimenggu, China; 6g, Linderae Radix (Wuyao in Chinese, No. Meanwhile, the result of the cell wound scratch assay showed a slower healing rate after GXZY treatment (Figure 8B), and the difference was statistically significant (Figure 8C). Invigorates the Blood, moves Qi and alleviates pain. Packaging: 100 g/bt. 當歸, 川芎, 桃仁, 牡丹皮, 赤芍, 烏藥, 延胡索, 炙甘草, 香附, 紅花, 枳殼, 茜草. English: Persica & Carthamus Combination. Filtering with the network topological parameters, when the degree is greater than twice the median (degree >24), we get the preliminary hub network (Figure 2A). Take 3 grams of powder or capsules 2-3 times a day, or as practitioners recommended.
Version of this formula to equal the standard daily dose. CHB chronic hepatitis B. DC Degree Connectivity. Chuan Xiong Gan Cao regulates and harmonizes all the other. Pain of all types from qi and blood stagnation - often combined with other more systemic formulas based on the individual. Like other traditional Chinese medicine prescriptions, GXZY is a multi-component, multi-target drug, which achieves a specific therapeutic effect by regulating the active targets of the molecular network in the body (Yu et al., 2018). Water was purified using a Milli-Q system (Millipore, Billerica, MA, United States). Liver Qi stagnation. From a Western Medicine standpoint, such patterns can give rise to a range of conditions such as scanty menstruation, menstrual cramps or absence of menstruation for instance.
Blood stasis Yes No. Dosage: According to Him-che Yeung in Handbook of Chinese Herbs and. These prepared pieces of botanical drugs were converted into granules, and we obtained a pair of GXZY granules at 16 g, and the specific drug preparation process was shown in Supplementary Table S1. The animal study was reviewed and approved by the Animal Research Ethics Board of Beijing university of Chinese medicine Dongzhimen Hospital (Approval No: 19-29).
About the item: Brand: Blue Poppy. The percentages of collagen fiber deposits were counted in 5 randomly selected fields of each stained section using Imagepro-plus 6. The Effect of Gexia Zhuyu Tang. Baicao Acu & Moxa Essences. For legal advice, please consult a qualified professional. The increased expression of MMP9 promotes the migration of LX-2 cells, which is related to upregulating phosphorylation of IκBα and p65 protein (Xu et al., 2016). Relieves pain caused by Blood Stasis.
65 g/(kg d) (Reagan-Shaw et al., 2008). Gene Ontology: Tool for the Unification of Biology. Wu Yao (Radix Linderae), 8. The qRT-PCR results in LX2 cells showed that GXZY could reduce the mRNA expression of MMP9, CASP3, and GAPDH compared with the control group (Figure 8D). Identification of the key target genes and their expression.
With Gan Cao, moderates spasms and relieves abdominal pain. The protein lysates were separated by 10% sodium dodecyl sulphates polyacrylamide gel and then electrophoretically transferred (Bio-Rad) onto the PVDF membrane (Amersham Biosciences, Uppsala, Sweden). 2023 Crane Herb Company. Category: Herbs that regulate Qi. With Yan Hu Suo, treats everything from Liver Qi Stagnation to Deep Blood Stasis with pain anywhere in the body including stabbing chest pain, distending pain in the breast, Cold pain in the epigastrium, pain due to bulging disorder in the lower body and dysmenorrhea. After blocking, membranes were incubated with the relevant primary antibodies anti-MMP9 (1:100) at 4°C overnight, and then were incubated with the secondary antibody goat anti-rabbit IgG antibody (1:2, 000) at room temperature for 1 h, ß-actin antibody (1:5, 000) for control. With Xiang Fu and Dang Gui, for dysmenorrhea from Qi Stagnation and Blood Stasis.
Custom Formula Order. Meridian affinity: Liver. The Stomach is a so-called "Fu" Organ.
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